HDAC8 Polyclonal Antibody
Product Specifications
Background
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors.
Abbreviation
HDAC8
UniProt
Q9BY41
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant protein of human HDAC8
Target
CDA07; CDLS5; HD 8; HD8; HDAC 8; Hdac8; HDAC8; HDACL 1; HDACL1; Histone deacetylase 8; Histone deacetylase like 1; MRXS6; RPD 3; RPD3; WTS
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Cardiovascular; Epigenetics and Nuclear Signaling; Stem Cells
Purification
Affinity purification
Concentration
0.7 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
42kDa
Citation 01
https://www.nature.com/articles/s41419-022-04901-x
Isotype
IgG
Available Sizes
Curated Selection
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