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Cry2 (BC054794) Mouse Recombinant Protein

Product Specifications

Background

This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by Clock/Arntl heterodimers but then represses this upregulation in a feedback loop using Per/Cry heterodimers to interact with Clock/Arntl. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. [provided by RefSeq, Feb 2014]

Overview

Purified recombinant protein of Mouse cryptochrome 2 (photolyase-like) (cDNA clone MGC:65642 IMAGE:6834104), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

AV006279; D130054K12Rik

Gene ID

12953

UniProt

Q9R194

Accession Number mRNA

BC054794

Chromosomal Location

2 E1

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

66.9 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Cry2

Species

Mouse

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/12953

Uniprot URL

https://www.uniprot.org/uniprot/Q9R194

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/BC054794

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