E3 ligase Ligand-Linker Conjugate 35

E3ligaseLigand-Linker Conjugate 35 is an adduct formed by the conjugation of an E3 ligase ligand with a linker, specifically composed of (S, R, S) -AHPC and its corresponding linker. The (S, R, S) -AHPC component is a von Hippel-Lindau (VHL) ligand derived from VH032, capable of recruiting VHL protein. E3ligaseLigand-Linker Conjugate 35 serves as a critical intermediate for the synthesis of complete PROTACs molecules.