F2 (NM_010168) Mouse Recombinant Protein
Product Specifications
Background
This gene encodes a vitamin K-dependent glycoprotein coagulation factor that plays an important role in the process of blood coagulation and hemostasis. The encoded protein is an inactive zymogen that undergoes enzymatic cleavage by the coagulation factor Xa to form an active serine protease that converts soluble fibrinogen to insoluble fibrin clot. Most of the mice lacking the encoded protein die at an embryonic stage due to defects in yolk sac vasculature, while the rare nenonates succumb to hemorrhage on the first postnatal day. [provided by RefSeq, Apr 2015]
Overview
Purified recombinant protein of Mouse coagulation factor II (F2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
Cf-2; Cf2; F; FII; prot; thro
Gene ID
14061
UniProt
P19221, Q3TJ94
Accession Number mRNA
NM_010168
Chromosomal Location
2 50.63 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
70.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
F2
Species
Mouse
Protein ID
NP_034298
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/14061
Uniprot URL
https://www.uniprot.org/uniprot/P19221
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_010168
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_034298
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