Wrap73 (NM_021499) Mouse Recombinant Protein
Product Specifications
Background
The SSX2IP:WRAP73 complex is proposed to act as regulator of spindle anchoring at the mitotic centrosome. Required for the centrosomal localization of SSX2IP and normal mitotic bipolar spindle morphology. Required for the targeting of centriole satellite proteins to centrosomes such as of PCM1, SSX2IP, CEP290 and PIBF1/CEP90. Required for ciliogenesis and involved in the removal of the CEP97:CCP110 complex from the mother centriole. Involved in ciliary vesicle formation at the mother centriole and required for the docking of vesicles to the basal body during ciliogenesis; may promote docking of RAB8A- and ARL13B-containing vesicles (By similarity) .[UniProtKB/Swiss-Prot Function]
Synonyms
2610044M17Rik; 5330425N03Rik; Dd57; Wdr8; Wrap73
Gene ID
59002
UniProt
Q9JM98
Accession Number mRNA
NM_021499
Chromosomal Location
4 E2
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
52.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Wrap73
Species
Mouse
Protein ID
NP_067474
Overview
Purified recombinant protein of Mouse WD repeat containing, antisense to Trp73 (Wrap73), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/59002
Uniprot URL
https://www.uniprot.org/uniprot/Q9JM98
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_021499
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_067474
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