Srgap1 (NM_001081037) Mouse Recombinant Protein
Product Specifications
Background
GTPase-activating protein for RhoA and Cdc42 small GTPases. Together with CDC42 seems to be involved in the pathway mediating the repulsive signaling of Robo and Slit proteins in neuronal migration. SLIT2, probably through interaction with ROBO1, increases the interaction of SRGAP1 with ROBO1 and inactivates CDC42 (By similarity) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse SLIT-ROBO Rho GTPase activating protein 1 (Srgap1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
4930572H05Rik; Arhgap13
Gene ID
117600
UniProt
D3YZW1
Accession Number mRNA
NM_001081037
Chromosomal Location
10 D2
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
124.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Srgap1
Species
Mouse
Protein ID
NP_001074506
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/117600
Uniprot URL
https://www.uniprot.org/uniprot/D3YZW1
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001081037
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001074506
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