Δ4-Dafachronic Acid-d3

Δ4-Dafachronic Acid-d3 is deuterium labeled Δ4-Dafachronic acid. Δ4-Dafachronic acid is an agonist of DAF-12 and a metabolite of cholesterol[1][2].

Product Specifications

UNSPSC

12352211

Target

Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Others

Field of Research

Metabolic Disease

Smiles

O=C1CC[C@]2(C(CC[C@@]3([C@@]2(CC[C@]4([C@]3(CC[C@@]4([C@H](C)CCCC(C(O)=O)C([2H])([2H])[2H])[H])[H])C)[H])[H])=C1)C

Molecular Formula

C27H39D3O3

Molecular Weight

417.64

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Amie L T Romney, et al. Temperature-dependent vitamin D signaling regulates developmental trajectory associated with diapause in an annual killifish. Proc Natl Acad Sci U S A. 2018 Dec 11;115 (50) :12763-12768.