Δ4-Dafachronic Acid-d3
Δ4-Dafachronic Acid-d3 is deuterium labeled Δ4-Dafachronic acid. Δ4-Dafachronic acid is an agonist of DAF-12 and a metabolite of cholesterol[1][2].
Product Specifications
UNSPSC
12352211
Target
Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Others
Field of Research
Metabolic Disease
Smiles
O=C1CC[C@]2(C(CC[C@@]3([C@@]2(CC[C@]4([C@]3(CC[C@@]4([C@H](C)CCCC(C(O)=O)C([2H])([2H])[2H])[H])[H])C)[H])[H])=C1)C
Molecular Formula
C27H39D3O3
Molecular Weight
417.64
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Amie L T Romney, et al. Temperature-dependent vitamin D signaling regulates developmental trajectory associated with diapause in an annual killifish. Proc Natl Acad Sci U S A. 2018 Dec 11;115 (50) :12763-12768.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Curated Selection
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