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Δ4-Dafachronic Acid-d3

Product Specifications

UNSPSC Description

Δ4-Dafachronic Acid-d3 is deuterium labeled Δ4-Dafachronic acid. Δ4-Dafachronic acid is an agonist of DAF-12 and a metabolite of cholesterol[1][2].

Target Antigen

Isotope-Labeled Compounds; Others

Type

Isotope-Labeled Compounds

Related Pathways

Others

Field of Research

Metabolic Disease

Smiles

O=C1CC[C@]2(C(CC[C@@]3([C@@]2(CC[C@]4([C@]3(CC[C@@]4([C@H](C)CCCC(C(O)=O)C([2H])([2H])[2H])[H])[H])C)[H])[H])=C1)C

Molecular Weight

417.64

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Amie L T Romney, et al. Temperature-dependent vitamin D signaling regulates developmental trajectory associated with diapause in an annual killifish. Proc Natl Acad Sci U S A. 2018 Dec 11;115(50):12763-12768.

Shipping Conditions

Room temperature

Clinical Information

No Development Reported

Curated Selection

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