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Gucy2e (NM_008192) Mouse Recombinant Protein

Product Specifications

Background

Catalyzes the synthesis of cyclic GMP (cGMP) in rods and cones of photoreceptors. Plays an essential role in phototransduction, by mediating cGMP replenishment (PubMed:21598940) . May also participate in the trafficking of membrane-asociated proteins to the photoreceptor outer segment membrane (PubMed:17255100) .[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse guanylate cyclase 2e (Gucy2e), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

GC-E; GC1; ROS-GC1

Gene ID

14919

UniProt

P52785

Accession Number mRNA

NM_008192

Chromosomal Location

11 42.51 cM

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

121.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Gucy2e

Species

Mouse

Protein ID

NP_032218

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/14919

Uniprot URL

https://www.uniprot.org/uniprot/P52785

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_008192

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_032218

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