FADD Recombinant Rabbit Monoclonal Antibody [PSH07-78]
FAS-associated death domain protein, also called MORT1, is encoded by the FADD gene on the 11q13.3 region of chromosome 11 in humans. FADD is an adaptor protein that bridges members of the tumor necrosis factor receptor superfamily, such as the Fas-receptor, to procaspases 8 and 10 to form the death-inducing signaling complex (DISC) during apoptosis. As well as its most well known role in apoptosis, FADD has also been seen to play a role in other processes including proliferation, cell cycle regulation and development.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
Fadd, Mort1
Swiss Prot
Q13158 Human, Q61160 Mouse,
Cellular Locus
Cytoplasm, cytosol, plasma membrane, ripoptosome.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Recombinant protein within mouse FADD aa 1-250.
Isotype
IgG
Clone
PSH07-78
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P
Positive Control
A431 cell lysate, NIH/3T3 cell lysate, RAW264.7 cell lysate, mouse colon tissue, rat colon tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1,000 ;IHC-P: 1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 23 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
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