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FADD Recombinant Rabbit Monoclonal Antibody [PSH07-78]

FAS-associated death domain protein, also called MORT1, is encoded by the FADD gene on the 11q13.3 region of chromosome 11 in humans. FADD is an adaptor protein that bridges members of the tumor necrosis factor receptor superfamily, such as the Fas-receptor, to procaspases 8 and 10 to form the death-inducing signaling complex (DISC) during apoptosis. As well as its most well known role in apoptosis, FADD has also been seen to play a role in other processes including proliferation, cell cycle regulation and development.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

FADD antibody FADD protein antibody FADD_HUMAN antibody Fas (TNFRSF6) associated via death domain antibody Fas associated via death domain antibody Fas associating death domain containing protein antibody Fas associating protein antibody Fas associating protein with death domain antibody Fas TNFRSF6 associated via death domain antibody FAS-associated death domain protein antibody FAS-associating death domain-containing protein antibody GIG 3 antibody GIG3 antibody Growth inhibiting gene 3 protein antibody Growth-inhibiting gene 3 protein antibody H sapiens mRNA for mediator of receptor induced toxicity antibody Mediator of receptor induced toxicity antibody MGC8528 antibody MORT 1 antibody MORT1 antibody Protein FADD antibody

Abbreviation

Fadd, Mort1

Swiss Prot

Q13158 Human, Q61160 Mouse,

Cellular Locus

Cytoplasm, cytosol, plasma membrane, ripoptosome.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Recombinant protein within mouse FADD aa 1-250.

Isotype

IgG

Clone

PSH07-78

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P

Positive Control

A431 cell lysate, NIH/3T3 cell lysate, RAW264.7 cell lysate, mouse colon tissue, rat colon tissue.

Concentration

1 mg/mL

Dilution

WB: 1:1,000 ;IHC-P: 1:1,000

Purity

Protein A affinity purified.

Form

Liquid

Buffer

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 23 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes

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