Unc13d (NM_001009573) Mouse Recombinant Protein
Selected Variant
PM42441M5
Size: 20 µg
Product Specifications
Background
Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse. Regulates assembly of recycling and late endosomal structures, leading to the formation of an endosomal exocytic compartment that fuses with perforin-containing granules at the immunologic synapse and licences them for exocytosis (By similarity) . Regulates Ca (2+) -dependent secretory lysosome exocytosis in mast cells.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse unc-13 homolog D (Unc13d), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
2610108D09Rik; Jinx; mFLJ00067; Munc13-4
Gene ID
70450
UniProt
B2RUP2, Q80UG7
Accession Number mRNA
NM_001009573
Chromosomal Location
11 E2
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
122.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Unc13d
Species
Mouse
Protein ID
NP_001009573
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/70450
Uniprot URL
https://www.uniprot.org/uniprot/B2RUP2
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001009573
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001009573
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