Filamin B Recombinant Rabbit Monoclonal Antibody [PSH07-34]
Filamin B, beta (FLNB), also known as Filamin B, beta (truncated actin binding protein 278 homolog), is a cytoplasmic protein which in humans is encoded by the FLNB gene. FLNB regulates intracellular communication and signalling by cross-linking the protein actin to allow direct communication between the cell membrane and cytoskeletal network, to control and guide proper skeletal development. Mutations in the FLNB gene are involved in several lethal bone dysplasias, including boomerang dysplasia and atelosteogenesis type I.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
FLNB, FLN1L, FLN3, TABP, TAP
Swiss Prot
O75369 Human, Q80X90 Mouse,
Cellular Locus
Cytoplasm, cell cortex, cytoskeleton, stress, myofibril, sarcomere, Z line.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Recombinant protein within human Filamin B aa
Isotype
IgG
Clone
PSH07-34
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, IF-Tissue
Positive Control
Concentration
1 mg/mL
Dilution
WB: 1:5,000 ;IHC-P: 1:5,000 ;IF-Tissue: 1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 278 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
Frequently Asked Questions
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