Erbb3 (NM_010153) Mouse Recombinant Protein
Product Specifications
Background
Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it; ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase. May also be activated by CSPG5. Involved in the regulation of myeloid cell differentiation.[UniProtKB/Swiss-Prot Function]
Synonyms
C76256; Erbb-3; Erbb3r; Her3
Gene ID
13867
UniProt
Q61526
Accession Number mRNA
NM_010153
Chromosomal Location
10 77.1 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
148.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Erbb3
Species
Mouse
Protein ID
NP_034283
Overview
Purified recombinant protein of Mouse erb-b2 receptor tyrosine kinase 3 (Erbb3), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/13867
Uniprot URL
https://www.uniprot.org/uniprot/Q61526
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_010153
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_034283
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