MTERFD1 Recombinant Mouse Monoclonal Antibody [A8-A10-R]
MTERFD1 belongs to the MTERF family which consists of four members including MTERF1, MTERF2, MTERF3 and MTERF4. Previous research showed that MTERFD1 is a mitochondrial protein that interacts with the mitochondrial DNA promoter region and decreases transcription initiation in mammalian mitochondria. This negative regulation is likely important for fine-tuning mitochondria transcription in response to physiological demands. Human mitochondrial transcription termination factor domain 1 (MTERFD1) was mutated in many types of cancer. In vivo and in vitro data indicated that MTERFD1 gene possesses oncogenic properties.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
mTERF3, MTERF3, MTERFD1, CGI-12
Swiss Prot
Q96E29 Human, Q8R3J4 Mouse
Cellular Locus
Mitochondrion.
Host
Mouse
Species Reactivity
Human,Mouse
Immunogen
Recombinant protein with Human MTERFD1 aa 29-417 / 417.
Isotype
IgG1
Clone
A8-A10-R
Conjugation
Non-conjugated
Type
Recombinant Mouse monoclonal Antibody
Applications
WB
Positive Control
Concentration
1 mg/mL
Dilution
WB: 1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 48 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
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