STIP1 (NM_006819) Human Recombinant Protein
Selected Variant
PH32676I1
Size: 20 µg
Product Specifications
Background
STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]) .[supplied by OMIM, Jul 2009]
Overview
Recombinant protein of human human stress-induced-phosphoprotein 1 (STIP1), full length, with N-terminal His tag, expressed in sf9 cells
Synonyms
HEL-S-94n; HOP; IEF-SSP-3521; P60; STI1; STI1L
Gene ID
10963
UniProt
P31948, V9HW72
Accession Number mRNA
NM_006819
Chromosomal Location
11q13.1
Expression System
Sf9
Tag
N-His
Related Pathways
Prion diseases
Field of Research
Prion diseases
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
50mM Tris-HCl, pH8.0, 100mM glycine, 10% glycerol
Function
Stem cell - Pluripotency
Molecular Weight
62.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
STIP1
Species
Human
Protein ID
NP_006810
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/10963
Uniprot URL
https://www.uniprot.org/uniprot/P31948
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_006819
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_006810
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