SHB (NM_003028) Human Recombinant Protein
Product Specifications
Background
Adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. May play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. May also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic-FGF and NGF-induced signaling cascades. May also regulate IRS1 and IRS2 signaling in insulin-producing cells.[UniProtKB/Swiss-Prot Function]
Synonyms
BA3J10.2
Gene ID
6461
UniProt
Q15464
Accession Number mRNA
NM_003028
Chromosomal Location
9p13.1
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.
Function
ES Cell Differentiation/IPS
Molecular Weight
54.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
SHB
Species
Human
Protein ID
NP_003019
Overview
Purified recombinant protein of Human Src homology 2 domain containing adaptor protein B (SHB), full length, with N-terminal HIS tag, expressed in E. coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/6461
Uniprot URL
https://www.uniprot.org/uniprot/Q15464
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_003028
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_003019
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