MAP1LC3B2 (NM_001085481) Human Recombinant Protein
Product Specifications
Background
Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes) . Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (By similarity) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Human microtubule-associated protein 1 light chain 3 beta 2 (MAP1LC3B2), full length, with N-terminal HIS tag, expressed in E. coli, 50ug
Synonyms
ATG8G
Gene ID
643246
UniProt
A6NCE7
Accession Number mRNA
NM_001085481
Chromosomal Location
12q24.22
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.
Molecular Weight
14.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
MAP1LC3B2
Species
Human
Protein ID
NP_001078950
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/643246
Uniprot URL
https://www.uniprot.org/uniprot/A6NCE7
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001085481
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001078950
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