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MAP1LC3B2 (NM_001085481) Human Recombinant Protein

Product Specifications

Background

Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes) . Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (By similarity) .[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Human microtubule-associated protein 1 light chain 3 beta 2 (MAP1LC3B2), full length, with N-terminal HIS tag, expressed in E. coli, 50ug

Synonyms

ATG8G

Gene ID

643246

UniProt

A6NCE7

Accession Number mRNA

NM_001085481

Chromosomal Location

12q24.22

Expression System

E. coli

Tag

N-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.

Molecular Weight

14.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

MAP1LC3B2

Species

Human

Protein ID

NP_001078950

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/643246

Uniprot URL

https://www.uniprot.org/uniprot/A6NCE7

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001085481

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001078950

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