USP22 (NM_015276) Human Recombinant Protein
Product Specifications
Background
Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation and cell cycle progression.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Human ubiquitin specific peptidase 22 (USP22), full length, with N-terminal HIS tag, expressed in E. coli, 50ug
Synonyms
USP3L
Gene ID
23326
UniProt
Q9UPT9
Accession Number mRNA
NM_015276
Chromosomal Location
17p11.2
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
50mM Tris, 8M Urea, pH8.0.
Function
Protease
Molecular Weight
59.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
USP22
Species
Human
Protein ID
NP_056091
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/23326
Uniprot URL
https://www.uniprot.org/uniprot/Q9UPT9
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_015276
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_056091
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