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EIF2B3 (NM_001166588) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]

Overview

Purified recombinant protein of Human eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa (EIF2B3), transcript variant 2, full length, with N-terminal HIS tag, expressed in E. coli, 50ug

Synonyms

EIF-2B; EIF2Bgamma

Gene ID

8891

UniProt

Q9NR50

Accession Number mRNA

NM_001166588

Chromosomal Location

1p34.1

Expression System

E. coli

Tag

N-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

50mM Tris, 8M Urea, pH8.0.

Molecular Weight

46.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

EIF2B3

Species

Human

Protein ID

NP_001160060

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/8891

Uniprot URL

https://www.uniprot.org/uniprot/Q9NR50

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001166588

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001160060

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