ChemR23 (R249) polyclonal antibody

Product Specifications

Background

Chemokine receptor-like 1 (also designated G protein-coupled receptor DEZ or ChemR23) belongs to the G protein-coupled receptor 1 family. It is an integral membrane protein functioning as a receptor, possibly a chemotactic peptide receptor. It also acts as a co-receptor for various SIV strains and for a primary HIV-1 strain. ChemR23 is highly expressed in developing osseous and cartilaginous tissue, brain, kidney, gastrointestinal tissues and myeloid tissue, as well as in adult parathyroid glands.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Chemokine-like receptor 1; G-protein coupled receptor; ChemR23; G-protein coupled receptor DEZ; CMKLR1; CHEMR23; DEZ

Swiss Prot

Q99788

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 216-265 of Human MChemR23.

Conjugation

Unconjugated

Applications

WB IHC IF

Dilution

WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 50 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

ChemR23 (R249) polyclonal antibody detects endogenous levels of ChemR23 protein.

Applications Notes

Western blot (WB) analysis of CMKLR1 pAb at 1:500 dilution Lane1:RAW264.7 whole cell lysate (40ug) Lane2:PMVEC whole cell lysate (40ug) Lane3:HUT78 whole cell lysate (40ug) Lane4:A549 whole cell lysate (40ug) Lane5:LO2 whole cell lysate (40ug)