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NDUFA11 (NM_175614) Human Recombinant Protein

Product Specifications

Background

This gene encodes a subunit of the membrane-bound mitochondrial complex I. Complex I is composed of numerous subunits and functions as the NADH-ubiquinol reductase of the mitochondrial electron transport chain. Mutations in this gene are associated with severe mitochondrial complex I deficiency. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2010]

Overview

Purified recombinant protein of Human NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa (NDUFA11), nuclear gene encoding mitochondrial protein, transcript variant 1, full length, with N-terminal GST and C-terminal HIS tag, expressed in E. coli, 50ug

Synonyms

B14.7; CI-B14.7; MC1DN14

Gene ID

126328

UniProt

Q86Y39

Accession Number mRNA

NM_175614

Chromosomal Location

19p13.3

Expression System

E. coli

Tag

N-GST and C-His

Related Pathways

Metabolic pathways, Oxidative phosphorylation

Field of Research

Metabolic pathways, Oxidative phosphorylation

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1%Sarkosyl.

Function

Transmembrane

Molecular Weight

42.7 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

NDUFA11

Species

Human

Protein ID

NP_783313

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/126328

Uniprot URL

https://www.uniprot.org/uniprot/Q86Y39

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_175614

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_783313

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