NDUFS7 (NM_024407) Human Recombinant Protein
Product Specifications
Background
This gene encodes a protein that is a subunit of one of the complexes that forms the mitochondrial respiratory chain. This protein is one of over 40 subunits found in complex I, the nicotinamide adenine dinucleotide (NADH) :ubiquinone oxidoreductase. This complex functions in the transfer of electrons from NADH to the respiratory chain, and ubiquinone is believed to be the immediate electron acceptor for the enzyme. Mutations in this gene cause Leigh syndrome due to mitochondrial complex I deficiency, a severe neurological disorder that results in bilaterally symmetrical necrotic lesions in subcortical brain regions. [provided by RefSeq, Jul 2008]
Overview
Purified recombinant protein of Human NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) (NDUFS7), nuclear gene encoding mitochondrial protein, full length, with N-terminal His tag, expressed in E. coli, 50ug
Synonyms
CI-20; CI-20KD; MC1DN3; MY017; PSST
Gene ID
374291
UniProt
O75251, Q7LD69
Accession Number mRNA
NM_024407
Chromosomal Location
19p13.3
Expression System
E. coli
Tag
N-His
Related Pathways
Alzheimer's disease, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease
Field of Research
Alzheimer's disease, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
50mM Tris, pH8.0, 8M Urea.
Molecular Weight
23.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
NDUFS7
Species
Human
Protein ID
NP_077718
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/374291
Uniprot URL
https://www.uniprot.org/uniprot/O75251
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_024407
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_077718
Frequently Asked Questions
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