SMC2 Recombinant Rabbit Monoclonal Antibody [PSH0-62]
Structural maintenance of chromosomes protein 2 (SMC-2), also known as chromosome-associated protein E (CAP-E), is a protein that in humans is encoded by the SMC2 gene. SMC2 is part of the SMC protein family and is a core subunit of condensin I and II, large protein complexes involved in chromosome condensation, overall organization. Several studies have demonstrated the necessity of SMC2 for cell division and proliferation. SMC2 works in the condensin complex as transcriptional regulation by compacting replicated DNA prior to mitotic division via supercoiling of the DNA. SMC2 also functions in resolving Sister chromatids prior to Anaphase.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
SMC2, CAPE, SMC2L1
Swiss Prot
O95347 Human
Cellular Locus
Nucleus, Cytoplasm, Chromosome.
Host
Rabbit
Species Reactivity
Human,Monkey
Immunogen
Recombinant protein within human SMC2 aa 451-750 / 1,197.
Isotype
IgG
Clone
PSH0-62
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, IF-Cell
Positive Control
Concentration
1 mg/mL
Dilution
WB: 1:1,000;IHC-P: 1:1,000;IF-Cell: 1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 136 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
Frequently Asked Questions
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