KLRC4 (NM_013431) Human Recombinant Protein
Product Specifications
Background
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. This gene is a member of the NKG2 group of genes that are expressed primarily in natural killer (NK) cells. These family members encode transmembrane proteins that are characterized by a type II membrane orientation (have an extracellular C-terminus) and the presence of a C-type lectin domain. This family member is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells. Read-through transcription exists between this gene and the downstream KLRK1 (killer cell lectin-like receptor subfamily K, member 1) family member. [provided by RefSeq, Dec 2010]
Overview
Purified recombinant protein of Human killer cell lectin-like receptor subfamily C, member 4 (KLRC4), full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug
Synonyms
NKG2-F; NKG2F
Gene ID
8302
UniProt
O43908
Accession Number mRNA
NM_013431
Chromosomal Location
12p13.2
Expression System
E. coli
Tag
N-GST and C-His
Related Pathways
Antigen processing and presentation
Field of Research
Antigen processing and presentation
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
50mM Tris, pH8.0, 8M Urea.
Function
Transmembrane
Molecular Weight
46.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
KLRC4
Species
Human
Protein ID
NP_038459
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/8302
Uniprot URL
https://www.uniprot.org/uniprot/O43908
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_013431
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_038459
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog