HJURP (NM_018410) Human Recombinant Protein
Product Specifications
Background
Centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres. Acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. Prevents CENPA-H4 tetramerization and prevents premature DNA binding by the CENPA-H4 tetramer. Directly binds Holliday junctions.[UniProtKB/Swiss-Prot Function]
Synonyms
FAKTS; hFLEG1; URLC9
Gene ID
55355
UniProt
Q8NCD3
Accession Number mRNA
NM_018410
Chromosomal Location
2q37.1
Expression System
E. coli
Tag
N-GST and C-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
50mM Tris, pH8.0, 8M Urea.
Function
Druggable Genome
Molecular Weight
111.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
HJURP
Species
Human
Protein ID
NP_060880
Overview
Purified recombinant protein of Human Holliday junction recognition protein (HJURP), full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/55355
Uniprot URL
https://www.uniprot.org/uniprot/Q8NCD3
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_018410
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_060880
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
