Recombinant ATP-Citrate Lyase Monoclonal Antibody
Product Specifications
Background
ATP citrate lyase (ACLY) Homo sapiens ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
Abbreviation
ATP-Citrate Lyase
UniProt
P53396
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Human ATP-Citrate Lyase protein
Target
OTTHUMP; ACLY; ACL; ATPCL; CLATP; ATP citrate (pro-S) lyase; ATP citrate lyase; ATP citrate synthase; ATP-citrate (pro-S-) -lyase; ATPcitrate synthase; ATP-citrate synthase; Citrate cleavage enzyme; OTTHUMP00000164773; ATP-citrate synthase
Clonality
Monoclonal,Recombinant
Clone
2D13
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Signal Transduction; Cancer; Metabolism
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
IHC 1:2000-1:10000; WB 1:2000-1:10000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product MSDS
https://789.bio/eb/OPMzijM5
Calculated Molecular Weight
121 kDa
Observed Molecular Weight
121 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
