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LYN (NM_002350) Human Recombinant Protein

Product Specifications

Background

This gene encodes a tyrosine protein kinase, which maybe involved in the regulation of mast cell degranulation, and erythroid differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]

Overview

Purified recombinant protein of Human tyrosine-protein kinase Lyn isoform A (LYN), Gly8-Asp238, with N-terminal HIS tag, expressed in E. coli, 50ug

Synonyms

JTK8; p53Lyn; p56Lyn

Gene ID

4067

UniProt

P07948, Q6NUK7, A8K379

Accession Number mRNA

NM_002350

Chromosomal Location

8q12.1

Expression System

E. coli

Tag

N-His

Related Pathways

B cell receptor signaling pathway, Chemokine signaling pathway, Epithelial cell signaling in Helicobacter pylori infection, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Long-term depression

Field of Research

B cell receptor signaling pathway, Chemokine signaling pathway, Epithelial cell signaling in Helicobacter pylori infection, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Long-term depression

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol

Function

Druggable Genome, Protein Kinase

Molecular Weight

26.5 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

LYN

Species

Human

Protein ID

NP_002341

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/4067

Uniprot URL

https://www.uniprot.org/uniprot/P07948

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_002350

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_002341

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