LYN (NM_002350) Human Recombinant Protein
Product Specifications
Background
This gene encodes a tyrosine protein kinase, which maybe involved in the regulation of mast cell degranulation, and erythroid differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]
Overview
Purified recombinant protein of Human tyrosine-protein kinase Lyn isoform A (LYN), Gly8-Asp238, with N-terminal HIS tag, expressed in E. coli, 50ug
Synonyms
JTK8; p53Lyn; p56Lyn
Gene ID
4067
UniProt
P07948, Q6NUK7, A8K379
Accession Number mRNA
NM_002350
Chromosomal Location
8q12.1
Expression System
E. coli
Tag
N-His
Related Pathways
B cell receptor signaling pathway, Chemokine signaling pathway, Epithelial cell signaling in Helicobacter pylori infection, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Long-term depression
Field of Research
B cell receptor signaling pathway, Chemokine signaling pathway, Epithelial cell signaling in Helicobacter pylori infection, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Long-term depression
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol
Function
Druggable Genome, Protein Kinase
Molecular Weight
26.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
LYN
Species
Human
Protein ID
NP_002341
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/4067
Uniprot URL
https://www.uniprot.org/uniprot/P07948
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_002350
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_002341
Frequently Asked Questions
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