Iduronate 2 sulfatase (IDS) Mouse Monoclonal Antibody [Clone ID: LBI4G2]

Product Specifications

Background

Iduronate-2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this X-chromosome gene that result in enzymatic deficiency lead to the sex-linked Mucopolysaccharidosis Type II, also known as Hunter Syndrome. Iduronate-2-sulfatase has a strong sequence similarity with human arylsulfatases A, B, and C, and human glucosamine-6-sulfatase. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq]

Overview

Carrier-free (BSA/glycerol-free) IDS mouse monoclonal antibody, clone LBI4G2

Synonyms

MPS2; SIDS

Gene Name

Homo sapiens iduronate 2-sulfatase (IDS), transcript variant 1, mRNA.

Gene ID

3423

UniProt

P22304

Conjugation

Unconjugated

Related Pathways

Glycosaminoglycan degradation, Lysosome, Metabolic pathways

Field of Research

Glycosaminoglycan degradation, Lysosome, Metabolic pathways

Dilution

WB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.