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AP2M1 Mouse Monoclonal Antibody [Clone ID: LBI1F10]

Product Specifications

Background

This gene encodes a subunit of the heterotetrameric coat assembly protein complex 2 (AP2), which belongs to the adaptor complexes medium subunits family. The encoded protein is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. The encoded protein may also play an important role in regulating the intracellular trafficking and function of CTLA-4 protein. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Overview

Carrier-free (BSA/glycerol-free) AP2M1 mouse monoclonal antibody, clone LBI1F10

Synonyms

AP50; CLAPM1; mu2

Gene Name

Homo sapiens adaptor related protein complex 2 subunit mu 1 (AP2M1), transcript variant 2, mRNA.

Gene ID

1173

UniProt

Q96CW1

Conjugation

Unconjugated

Related Pathways

Endocytosis, Huntington's disease

Field of Research

Endocytosis, Huntington's disease

Dilution

WB 1:2000, IF 1:100, FLOW 1:100

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

AP2M1

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=1173

Uniprot URL

https://www.uniprot.org/uniprot/Q96CW1

Frequently Asked Questions

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