Recombinant Human GCDH Protein (His Tag)
Product Specifications
Background
Glutaryl-CoA Dehydrogenase Mitochondrial (GCDH) is an enzyme that acts upon glutaryl-coenzyme A, creating crotonyl-coenzyme A. It plays a role in the metabolism of lysine, hydroxylysine and tryptophan. It uses electron transfer flavoprotein as its electron acceptor. Isoform Short is inactive Glutaryl-CoA and electron-transfer flavoprotein to (E) -but-2-enoyl-CoA, CO2 and reduced electron-transfer flavoprotein. A defect in this enzyme is associated with neurological condition glutaric acidemia type 1 and cause a progressive form of early-onset generalized dystonia.
Abbreviation
GCDH
Synonyms
GCD; GCDH; Glutaryl-CoA Dehydrogenase Mitochondrial
UniProt
Q92947
Accession Number
Q92947
Expression System
E.coli
Tag
N-His
Sequence
Arg45-Lys438
Field of Research
Signal Transduction; Tags & Cell Markers; Cancer; metabolism
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
45.0 kDa
Observed Molecular Weight
41 kDa
Formulation
Supplied as a 0.2 μm filtered solution of 20mM HEPES, 150mM NaCl, pH 7.4.
Species
Human
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
LY420469 100 µg
TMEM100 (NM_001099640) Human Over-expression Lysate
Sign In for Pricing
View Details 
1955-AAT 2 Labelings
ReadiLink™ xtra Rapid iFluor® 488 Antibody Labeling Kit *BSA-Compatible*
Sign In for Pricing
View Details