KEAP1 Mouse Monoclonal Antibody [Clone ID: LBI1B4]

Product Specifications

Background

This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq]

Overview

Carrier-free (BSA/glycerol-free) KEAP1 mouse monoclonal antibody, clone LBI1B4

Synonyms

INrf2; KLHL19

Gene Name

Homo sapiens kelch like ECH associated protein 1 (KEAP1), transcript variant 1, mRNA.

Gene ID

9817

UniProt

Q14145

Conjugation

Unconjugated

Related Pathways

Ubiquitin mediated proteolysis

Field of Research

Ubiquitin mediated proteolysis

Dilution

WB 1:500~2000, IHC 1:150, FLOW 1:100

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Transcription Factors

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.