Anti-Noggin Antibody

Our Noggin rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects human, mouse, and rat Noggin and is antigen affinity purified. It is great for use in WB.

Product Specifications

Background

Noggin is involved in numerous developmental processes, such as neural tube fusion and joint formation. The morphogenesis of organs is initiated by a downgrowth from a layer of epithelial stem cells. This process is achieved through the receipt of signals from 1) a WNT protein (WNT3A) to stabilize beta-catenin; and 2) Noggin, which is a bone morphogenetic protein inhibitor. Noggin mutations in unrelated families with proximal symphalangism (SYM1) and multiple synostoses syndrome (SYNS1) have been identified, which have multiple joint fusion as their principal defect.

Synonyms

NOG

Other Statements

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Gene Name

NOG

UniProt

Q13253

Host

Rabbit

Reactivity

Human, Mouse, and Rat

Immunogen

Synthetic peptide corresponding to amino acids from an internal sequence of the human Noggin protein.

Immunogen Type

Human

Target

Noggin

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

Format

Antigen Affinity Purified

Form

Liquid

Buffer

PBS + 0.02% NaN3

Shipping Conditions

Blue Ice

Storage Conditions

Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.