Cryptochrome I (CRY1) Mouse Monoclonal Antibody [Clone ID: LBI2F5]

Product Specifications

Background

This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Loss of the related gene in mouse results in a shortened circadian cycle in complete darkness. [provided by RefSeq, Jan 2014]

Overview

Carrier-free (BSA/glycerol-free) CRY1 mouse monoclonal antibody, clone LBI2F5

Synonyms

PHLL1

Gene Name

Homo sapiens cryptochrome circadian regulator 1 (CRY1), mRNA.

Gene ID

1407

UniProt

Q16526

Conjugation

Unconjugated

Related Pathways

Circadian rhythm - mammal

Field of Research

Circadian rhythm - mammal

Dilution

WB 1:2000

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.