mCMY416
Product Specifications
UNSPSC Description
mCMY416 is an orally active and blood brain barrier (BBB) permeability apicomplexan phenylalanine tRNA synthetase inhibitor, and shows antiparasitic activity [1].
Target Antigen
Aminoacyl-tRNA Synthetase; Parasite
Type
Reference compound
Related Pathways
Anti-infection;Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/mcmy416.html
Smiles
[H][C@]1([C@@H](C2=CC=C(C#CC3=CCCCC3)C=C2)CC4)N4CCCN(C(NC5=CC=C(OC)C=C5)=O)C1
Molecular Weight
469.62
References & Citations
[1]Ence CC, et al. Bicyclic pyrrolidine inhibitors of Toxoplasma gondii phenylalanine t-RNA synthetase with antiparasitic potency in vitro and brain exposure. Preprint. bioRxiv. 2024;2024.02.28.582607. Published 2024 Feb 28. |[2]Ence CC, et al. Bicyclic pyrrolidine inhibitors of Toxoplasma gondii phenylalanine t-RNA synthetase with antiparasitic potency in vitro and brain exposure. Preprint. bioRxiv. 2024;2024.02.28.582607. Published 2024 Feb 28.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-161666/mCMY416-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-161666/
Clinical Information
No Development Reported
Curated Selection
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