SIRT1 Mouse Monoclonal Antibody [Clone ID: LBI12H3]
Product Specifications
Background
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008]
Synonyms
SIR2; SIR2alpha; SIR2L1
Gene Name
Homo sapiens sirtuin 1 (SIRT1), transcript variant 1, mRNA.
Gene ID
23411
UniProt
Q96EB6
Conjugation
Unconjugated
Dilution
WB 1:2000
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome, Stem cell - Pluripotency, Transcription Factors
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
SIRT1
Overview
Carrier-free (BSA/glycerol-free) SIRT1 mouse monoclonal antibody, clone LBI12H3
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=23411
Uniprot URL
https://www.uniprot.org/uniprot/Q96EB6
Curated Selection
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