HDAC8 Mouse Monoclonal Antibody [Clone ID: LBI9F2]
Product Specifications
Background
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
Synonyms
CDA07; CDLS5; HD8; HDACL1; MRXS6; RPD3; WTS
Gene Name
Homo sapiens histone deacetylase 8 (HDAC8), transcript variant 1, mRNA.
Gene ID
55869
UniProt
Q9BY41
Conjugation
Unconjugated
Dilution
WB 1:2000
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome, Transcription Factors
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
HDAC8
Overview
Carrier-free (BSA/glycerol-free) HDAC8 mouse monoclonal antibody, clone LBI9F2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=55869
Uniprot URL
https://www.uniprot.org/uniprot/Q9BY41
Curated Selection
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