URP2 (FERMT3) Mouse Monoclonal Antibody [Clone ID: LBI3C7]
Product Specifications
Background
Kindlins are a small family of proteins that mediate protein-protein interactions involved in integrin activation and thereby have a role in cell adhesion, migration, differentiation, and proliferation. The protein encoded by this gene has a key role in the regulation of hemostasis and thrombosis. This protein may also help maintain the membrane skeleton of erythrocytes. Mutations in this gene cause the autosomal recessive leukocyte adhesion deficiency syndrome-III (LAD-III) . Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2010]
Synonyms
KIND3; MIG-2; MIG2B; UNC112C; URP2; URP2SF
Gene Name
Homo sapiens FERM domain containing kindlin 3 (FERMT3), transcript variant URP2SF, mRNA.
Gene ID
83706
UniProt
Q86UX7
Conjugation
Unconjugated
Dilution
WB 1:2000, IHC 1:150
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
FERMT3
Overview
Carrier-free (BSA/glycerol-free) FERMT3 mouse monoclonal antibody, clone LBI3C7
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=83706
Uniprot URL
https://www.uniprot.org/uniprot/Q86UX7
Curated Selection
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