Caspase 4 (CASP4) Mouse Monoclonal Antibody [Clone ID: LBI4A2]
Product Specifications
Background
This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
Synonyms
ICE (rel) II; ICEREL-II; ICH-2; Mih1; Mih1/TX; TX
Gene Name
Caspase 4
Gene ID
837
UniProt
P49662
Conjugation
Unconjugated
Concentration
1 mg/ml
Dilution
WB 1:2000
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome, Protease
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
CASP4
Overview
CASP4 mouse monoclonal antibody, clone LBI4A2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=837
Uniprot URL
https://www.uniprot.org/uniprot/P49662
Curated Selection
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