SNAP25 Mouse Monoclonal Antibody [Clone ID: LBI4B5]

Product Specifications

Background

Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs) . The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore, this gene product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. Two alternative transcript variants encoding different protein isoforms have been described for this gene. [provided by RefSeq]

Overview

SNAP25 mouse monoclonal antibody, clone LBI4B5

Synonyms

CMS18; RIC-4; RIC4; SEC9; SNAP; SNAP-25; SUP; bA416N4.2; dJ1068F16.2

Gene Name

Synaptosome associated protein 25

Gene ID

6616

UniProt

P60880

Conjugation

Unconjugated

Related Pathways

SNARE interactions in vesicular transport

Field of Research

SNARE interactions in vesicular transport

Concentration

1.1 mg/ml

Dilution

WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.