CLDN8 Antibody (Center) [AMM08582G]
Product Specifications
Background
Tissue Location: Expressed in the epididymis, mainly in the caput segment.
Synonyms
Claudin-8, CLDN8
Gene Name
HGNC:2050
Gene ID
9073
UniProt
P56748
Chromosomal Location
Cell junction, tight junction. Cell membrane {ECO:0000250|UniProtKB:Q9Z260}; Multi-pass membrane protein. Note=Localizes to tight junctions in all 3 segments of the epididymis, in the caput found in the lateral margins of principal cells, and in the corpus at the interface between basal and principal cells.
Applications
WB, FC
Dilution
WB--1:1000 FC--1:10~50
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Tight-junction protein required for paracellular chloride transport in the kidney. Mediates recruitment of CLDN4 to tight junction in the kidney. Claudins play a major role in tight junction- specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity.
Molecular Weight
24845
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CLDN8 Antibody (Center) [AMM08582G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=9073
Uniprot URL
https://www.uniprot.org/uniprot/P56748
Available Sizes
Curated Selection
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