RASSF1 Mouse Monoclonal Antibody [Clone ID: LBI9F5]

Product Specifications

Background

This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Several alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq]

Overview

RASSF1 mouse monoclonal antibody, clone LBI9F5

Synonyms

123F2; NORE2A; RASSF1A; RDA32; REH3P21

Gene Name

Ras association domain family member 1

Gene ID

11186

UniProt

Q9NS23

Conjugation

Unconjugated

Related Pathways

Bladder cancer, Non-small cell lung cancer, Pathways in cancer

Field of Research

Bladder cancer, Non-small cell lung cancer, Pathways in cancer

Concentration

0.97 mg/ml

Dilution

WB 1:2000, IF 1:100, FLOW 1:100

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.