Adinazolam

Adinazolam (U 41123) is a triazolobenzodiazepine. Adinazolam binds to peripheral-type benzodiazepine receptors which interact allosterically with GABA receptors. Adinazolam has dual anxiolytic and antidepressant activities[1][2][3].

Product Specifications

CAS Number

[37115-32-5]

Product Name Alternative

U 41123

UNSPSC

12352005

Hazard Statement

H225, H370

Target

GABA Receptor

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/adinazolam.html

Purity

99.0

Solubility

H2O : 1 mg/mL (ultrasonic;warming)

Smiles

CN(C)CC1=NN=C2N1C3=CC=C(Cl)C=C3C(C4=CC=CC=C4)=NC2

Molecular Formula

C19H18ClN5

Molecular Weight

351.83

Precautions

H225, H370

References & Citations

[1]P A Broderick.Adinazolam affects biogenic amine release in hippocampal CA1 neuronal circuitry.Brain Res Bull. 1991 Nov;27 (5) :689-92.|[2]R M Escorihuela, et al. Flumazenil prevents the anxiolytic effects of diazepam, alprazolam and adinazolam on the early acquisition of two-way active avoidance. Pharmacol Res. Jul-Aug 1993;28 (1) :53-8.|[3]Adinazolam.