IBRDC2 (RNF144B) Mouse Monoclonal Antibody [Clone ID: LBI10A12]
Product Specifications
Background
E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2, thereby promoting their degradation. Induces apoptosis via a TP53/p53-dependent but caspase-independent mechanism.
Overview
RNF144B (IBRDC2) mouse monoclonal antibody, clone LBI10A12
Synonyms
BA528A10.3; IBRDC2; p53RFP; PIR2
Gene Name
Ring finger protein 144B
Gene ID
255488
UniProt
Q7Z419
Conjugation
Unconjugated
Concentration
1 mg/ml
Dilution
WB 1:100
Form
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Transmembrane
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
RNF144B
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=255488
Uniprot URL
https://www.uniprot.org/uniprot/Q7Z419
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