MIB2 Antibody (N-Term) [APR33449G]

Product Specifications

Background

Tissue Location: Expressed in skeletal muscle, and to a lesser extent in heart, brain and kidney.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MIB2 Antibody (N-Term) [APR33449G].

Synonyms

E3 ubiquitin-protein ligase MIB2, 6.3.2.-, Mind bomb homolog 2, Novel zinc finger protein, Novelzin, Putative NF-kappa-B-activating protein 002N, Skeletrophin, Zinc finger ZZ type with ankyrin repeat domain protein 1, MIB2, SKD, ZZANK1

Gene Name

MIB2

Gene ID

142678

UniProt

Q96AX9

Chromosomal Location

Cytoplasm. Endosome. Note=Colocalizes with endosomal compartments

Applications

Dilution

WB--1:1000

Function

E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors.

Molecular Weight

109939

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.