MIB2 Antibody (N-Term) [APR33449G]
Product Specifications
Background
Tissue Location: Expressed in skeletal muscle, and to a lesser extent in heart, brain and kidney.
Synonyms
E3 ubiquitin-protein ligase MIB2, 6.3.2.-, Mind bomb homolog 2, Novel zinc finger protein, Novelzin, Putative NF-kappa-B-activating protein 002N, Skeletrophin, Zinc finger ZZ type with ankyrin repeat domain protein 1, MIB2, SKD, ZZANK1
Gene Name
MIB2
Gene ID
142678
UniProt
Q96AX9
Chromosomal Location
Cytoplasm. Endosome. Note=Colocalizes with endosomal compartments
Applications
WB
Dilution
WB--1:1000
Function
E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors.
Molecular Weight
109939
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MIB2 Antibody (N-Term) [APR33449G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=142678
Uniprot URL
https://www.uniprot.org/uniprot/Q96AX9
Available Sizes
Curated Selection
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