(Mouse) Suz12 Antibody (Center) [APR33073G]
Product Specifications
Background
Tissue Location: Expressed in embryonic stem cells.
Synonyms
Polycomb protein Suz12, Suppressor of zeste 12 protein homolog, Suz12, D11Ertd530e, Kiaa0160
Gene Name
Suz12
Gene ID
52615
UniProt
Q80U70
Chromosomal Location
Nucleus. Chromosome. Note=Localizes to the inactive X chromosome in trophoblast stem cells
Applications
WB, IHC-P
Dilution
IHC-P--1:100~500 WB--1:2000
Function
Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems (By similarity) . Genes repressed by the PRC2/EED- EZH2 complex include HOXA7, HOXB6 and HOXC8.
Molecular Weight
83026
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality (Mouse) Suz12 Antibody (Center) [APR33073G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=52615
Uniprot URL
https://www.uniprot.org/uniprot/Q80U70
Available Sizes
Curated Selection
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