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Y11

Y11 inhibits FAK1 autophosphorylation by blocking phosphorylation of Y397 and decreases tumor growth[1].

Product Specifications

CAS Number

1086639-59-9

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

FAK

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/y11.html

Purity

98.34

Solubility

DMSO : 10 mg/mL (ultrasonic; warming)

Smiles

OCC[N+]12C[N@](C3)C[N@](C[N@]3C2)C1.[Br-]

Molecular Formula

C8H17BrN4O

Molecular Weight

265.15

Precautions

H315, H319, H335

References & Citations

[1]Golubovskaya VM, et al. A small molecule inhibitor, 1,2,4,5-benzenetetraamine tetrahydrochloride, targeting the y397 site of focal adhesion kinase decreases tumor growth. J Med Chem. 2008 Dec 11;51 (23) :7405-16.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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