GSN Antibody (C-term) [APR32416G]

Product Specifications

Background

Tissue Location: Phagocytic cells, platelets, fibroblasts, nonmuscle cells, smooth and skeletal muscle cells

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GSN Antibody (C-term) [APR32416G].

Synonyms

Gelsolin, AGEL, Actin-depolymerizing factor, ADF, Brevin, GSN

Gene Name

GSN

Gene ID

2934

UniProt

P06396

Chromosomal Location

[Isoform 2]: Cytoplasm, cytoskeleton.

Applications

IHC-P, FC, WB

Dilution

WB--1:1000-1:2000 IHC-P--1:100~500 FC--1:10~50

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Function

Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping) . It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis.