CID-663143
CID-663143 targets microtubule-associated proteins, not tubulin itself, to inhibit the polymerization process within cells. CID-663143 inhibits cancer cell growth (IC50: [1].
Product Specifications
UNSPSC
12352005
Target
Microtubule/Tubulin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cid-663143.html
Solubility
10 mM in DMSO
Smiles
COC1=C(C=CC=C1)C2=NN=C3SCC(C4=CC=C(OCC)C=C4)=NN23
Molecular Formula
C19H18N4O2S
Molecular Weight
366.44
References & Citations
[1]Yang WS, et al. Identification of Simple Compounds with Microtubule-Binding Activity That Inhibit Cancer Cell Growth with High Potency. ACS Med Chem Lett. 2012 Jan 12;3 (1) :35-38.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-121085/CID-663143-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-121085/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
CAS Number
[578723-96-3]
Available Sizes
Curated Selection
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