Tryptamine guanosine carbamate
Tryptamine guanosine carbamate (TpGc) is a selective HINT1 (histidine triad nucleotide-binding protein 1) inhibitor (Ki=34 μM, Kd=3.65 μM) . Tryptamine guanosine carbamate significantly enhances morphine antinociception while preventing the development of tolerance[1].
Product Specifications
CAS Number
[1414808-96-0]
Product Name Alternative
TpGc
UNSPSC
12352005
Target
DNA/RNA Synthesis; Tyrosinase
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/tryptamine-guanosine-carbamate.html
Purity
99.79
Solubility
DMSO : 125 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O[C@H]1[C@@H](O)[C@H](N2C3=C(C(N=C(N3)N)=O)N=C2)O[C@@H]1COC(NCCC4=CNC5=CC=CC=C45)=O
Molecular Formula
C21H23N7O6
Molecular Weight
469.45
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Available Sizes
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