DTX3L Antibody (Center) [APR31413G]

Product Specifications

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DTX3L Antibody (Center) [APR31413G].

Synonyms

E3 ubiquitin-protein ligase DTX3L, 632-, B-lymphoma- and BAL-associated protein, Protein deltex-3-like, Rhysin-2, Rhysin2, DTX3L, BBAP

Gene Name

DTX3L

Gene ID

151636

UniProt

Q8TDB6

Chromosomal Location

Cytoplasm. Nucleus. Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Lysosome membrane; Peripheral membrane protein; Cytoplasmic side. Note=Translocates to the nucleus in response to IFNG or IFNB1 stimulation (PubMed:26479788) . Localizes at sites of DNA damage in a PARP1-dependent manner (PubMed:23230272) Localization to early endosomes is increased upon CXCL12 stimulation where it co-localizes with ITCH, CXCL4, HGS and STAM (PubMed:24790097) A minor proportion localizes to lysosomes (PubMed:24790097)

Applications

Dilution

WB--1:1000

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.